Cutaneous Manifestations of Renal Failure in Khartoum Renal Centre in Khartoum, Sudan

摘要

Introduction: This study was done at Khartoum renal Centre (KRC), Khartoum, with Bahri University, Department of Dermatology and Venereology in 200 patients with renal failure, during the period from June 3 - October 28, 2001. The Objective: this study was to identify the frequency of the common cutaneous manifestations in patients with renal failure attending KRC. Patients & methodology: The design was based on the clinical study, i.e., descriptive. 200 cases of renal failure from different causes were seen, 50 out them were pre-dialysis, 100 were on regular hemodialysis and 50 were transplant recipients. Conclusions: This study revealed that 83.5% of RF patients examined have Cutaneous Manifestations (CMs). The showed that most of the CMs seen in patients on regular haemodialysis 89%, transplant recipients 84%, and then pre-dialysis patients 72%. This study showed that males represent 58%, and 51.5% of CMs are in the age group above 45 years. The common symptoms represented in this study, hyperpigmentations 83.2%, pruritus 70.6%, and xerosis 50.9% respectively. In the examination according to lesions morphology, hyperpigmented macules 81.4%, patches 52.1%, while plaques 1.2%, and bullae 0.6% represents in frequency. The most commonly associated diseases with RF were hypertension 64.1%, DM 7.2%, and gout 2.4% respectively. In this study, fungal infections of the nails, pityriasis versicoloured, Kaposi, s sarcoma, and Herpes zoster are observed mainly in transplant recipients patients. This study showed that socioeconomic factors have no prominent role affecting CM of RF, as well as drugs used in the treatment of RF. Thus, it was concluded that; CMs were detected in this study, 83.5% out of study population, hyperpigmentation represents 83.2%, hyperpigmented macules show 81.4%, fungal nail infections represent the highest presentation 22.8%, and then Kaposi’s sarcoma and Herpes zoster represents 1.8 & 1.2% respectively. Some of known CM of RF as dermatosis of dialysis, perforating collagenous, and cutaneous calcification not encountered in this study.