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首页> 外文期刊>Acta scientiarum. Health sciences. >Histologic and histomorphometric study of bone repair around short dental implants inserted in rabbit tibia, associated with tricalcium phosphate graft bone
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Histologic and histomorphometric study of bone repair around short dental implants inserted in rabbit tibia, associated with tricalcium phosphate graft bone

机译:组织学和组织形态计量学研究在胫骨中插入短牙种植体并与磷酸三钙移植骨相关的骨修复

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摘要

The use of short dental implants represents one way to overcome this limitation, in association with bone grafting procedures. Tricalcium phosphate-based grafts are among those widely used. The purpose of this study was to assess the biocompatibility of this biomaterial in the coverage of bone defects around short dental implants. Ten New Zealandrabbits were used in this study, each animal received 4 implants, two were placed in the right tibia region (control group) and two in the left tibia region (test group). Forty implants were used, with 4mm diameter and 6mm length. For the control group, holes 6 mmdeep were made, and the implants were then inserted at the level of bone tissue. In the control group, the implants of 6 mmin length were inserted to its full length, while in the test group, the same implant was inserted up to 4 mmand left exposed 2 mm. These 2 mmexposed were coated with a bone substitute of tricalcium phosphate and a collagen membrane. After three months, the animals were prepared for histomorphometric analysis, which showed that the control group had a higher number of osteoblasts per μm 2 than the test group (p < 0.001). It was concluded that under these experimental conditions, tricalcium phosphate showed tissue biocompatibility and osteoconductive potential.
机译:短牙种植体的使用代表了克服这一限制的一种方法,与骨移植程序相关。基于磷酸三钙的移植物是广泛使用的那些。这项研究的目的是评估这种生物材料在覆盖短牙种植体周围的骨缺损中的生物相容性。在该研究中使用了十只新西兰兔,每只动物接受了4个植入物,其中两个放在右胫骨区域(对照组),另外两个放在左胫骨区域(测试组)。使用了40个直径为4mm,长度为6mm的植入物。对于对照组,打6毫米深的孔,然后将植入物插入骨组织水平。在对照组中,将长度为6毫米的植入物插入其全长,而在测试组中,将相同的植入物插入至4毫米,并裸露2毫米。将这2mm暴露的骨用磷酸三钙的骨替代物和胶原膜覆盖。三个月后,准备对动物进行组织形态分析,结果表明,对照组的每μm2的成骨细胞数量比试验组的高(p <0.001)。结论是在这些实验条件下,磷酸三钙表现出组织生物相容性和骨传导潜力。

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