Comparison of drug-eluting and bare metal stents for extracranial vertebral artery stenting

摘要

Introduction Drug-eluting stents of the first (DES I) and second generation (DES II) proved superior to bare metal stents (BMS) in the coronary territory. However, there are limited data on whether they have any advantage over BMS in vertebral artery stenosis (VAS). Aim To compare outcomes of DES (DES I, DES II) and BMS in the treatment of symptomatic extracranial VAS. Material and methods During 13-year study period (2003–2016), 392 consecutive patients underwent VAS angioplasty in 428 arteries, including implantation of 148 DES (DES I: 21; DES II: 127 lesions), and 280 BMS. Results The technical success rates for DES and BMS groups were 96.7% and 94.6% (p = 0.103), with similar periprocedural complication rates (1.4% vs. 2.2%; p = 0.565). VAS degree was reduced from 86 ±9.7 to 2.7 ±5.0% in DES (p 5 mg/l (p = 0.043), while greater stent length was associated with ISR only in the DES group (p = 0.024). Conclusions Our results do not support significant differences in ISR/ISO rates between DES and BMS, although differences between particular stent types and ISR rates require further investigation.