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A multi-regions discrete-time epidemic model with a travel-blocking vicinity optimal control approach on patches

机译:在斑块上具有旅行阻塞附近最优控制方法的多区域离散时间流行病模型

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We study, in this paper, infection dynamics when an epidemic emerges to many regions which are connected with their neighbors by any kind of anthropological movement. For this, we devise a multi-regions discrete-time model with the three classical SIR compartments, describing the spatial-temporal behaviors of homogenous susceptible, infected and removed populations. We suppose a large geographical domain, presented by a grid of colored cells, to exhibit at each instant i the spatial propagation of an epidemic which affects its different parts or sub-domains that we call here cells or regions. In order to minimize the number of infected individuals in some regions, we suggest an optimal control approach based on a travel-blocking vicinity strategy which aims to control a group of cells, or a patch, by restricting movements of infected people coming from its neighboring cells. We apply a discrete version of Pontryagin’s maximum principle to state the necessary conditions and characterization of the travel-blocking optimal controls. We provide cellular simulations based on discrete progressive-regressive iterative schemes associated with the obtained multi-points boundary value problems. For illustrating the modeling and optimal control approaches, we consider an example of 100 regions.
机译:在本文中,我们研究了当流行病扩散到许多通过任何人类学运动与其邻居联系的区域时,感染的动态。为此,我们设计了具有三个经典SIR隔室的多区域离散时间模型,该模型描述了同质易感,感染和移出种群的时空行为。我们假设一个大的地理区域(由有色细胞的网格表示)在每个时刻展示一种流行病的空间传播,这种流行病会影响其不同部分或子域(在这里称为细胞或区域)。为了最大程度地减少某些地区的受感染个体数量,我们建议基于旅行阻止附近策略的最佳控制方法,该策略旨在通过限制来自附近地区的受感染者的活动来控制一组细胞或斑块细胞。我们采用了庞特里亚金最大原理的离散形式,以陈述必要的条件和行程限制最佳控制的特性。我们基于与获得的多点边值问题相关的离散渐进-迭代迭代方案提供了单元格模拟。为了说明建模和最佳控制方法,我们以100个区域为例。

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