A CASE REPORT OF MODERN MANAGEMENT OF ACROMEGALY

摘要

The management of acromegaly has improved in the last few years, offering new perspectives, particularly of patients with challenging tumors. We report a case of a male patient with acromegaly secondary to a growth hormone-secreting pituitary macroadenoma, with transsphenoidal selective surgical excision of the pituitary mass, followed by tumor recurrence. Since optimal therapeutic control was not achieved by long-acting somatostatin analog monotherapy after neurosurgery, the patient was recommended combined treatment with a somatostatin analog and a dopamine agonist, with incomplete response to therapy, attaining insulin-like growth factor 1 control only with combined therapy with a long-acting somatostatin analog and a growth hormone receptor antagonist.