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Clinical approach and treatment of benign and malignant parotid masses, personal experience

机译:腮腺良恶性肿块的临床处理方法,个人经验

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Parotid gland tumours account for 80% of all salivary gland neoplasms, 20% of these are malignant, but in daily clinical practice most parotid masses are operated on before obtaining the final histological diagnosis. This clinical setting further complicates the critical point of parotid surgery, which is the management of the facial nerve. In the present study, data were evaluated referring to 540 patients who underwent parotidectomy for a mass which was discovered to be a benign (470 cases) or a malignant (70 cases) neoplasm, between November 1994 and December 2007, at our Institution. The most significant single parameter in this series of malignancies regarding disease specific survival was the clinical involvement of the facial nerve at diagnosis (p = 0.006). Also for this reason, as there is no evidence that liberal VIIth nerve sacrifice improves prognosis, when it is not clinically involved, every attempt is made to dissect and preserve it. At present, the most complicated situation concerning nerve preservation may be, on the other hand, recurrence of a benign tumour, in particular pleomorphic adenoma, which, in our series, has a higher incidence (8.3%) of permanent facial dysfunction, than surgery with nerve preservation for malignancy (3.7%).
机译:腮腺肿瘤占所有唾液腺肿瘤的80%,其中20%是恶性的,但是在日常临床实践中,大多数腮腺肿块在获得最终的组织学诊断之前均已接受手术。这种临床情况使腮腺手术的关键点变得复杂,这是面神经的管理。在本研究中,我们对1994年11月至2007年12月间540例接受腮腺切除术的肿块进行了评估,这些肿块被发现为良性(470例)或恶性(70例)肿瘤。该系列恶性肿瘤中与疾病特异性生存有关的最重要的单个参数是诊断时面神经的临床受累(p = 0.006)。同样由于这个原因,因为没有证据表明第VII自由神经牺牲可以改善预后,所以在临床上不涉及时,会尽一切努力进行解剖和保存。目前,关于神经保存的最复杂情况可能是良性肿瘤的复发,特别是多形性腺瘤,在我们的系列研究中,其永久性面部功能障碍的发生率(8.3%)高于外科手术保留神经用于恶性肿瘤(3.7%)。

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