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首页> 外文期刊>Acta Biomedica Scientifica >Микроэкологическая и ассоциативная структура кишечного биоценоза детей с функциональными нарушениями пищеварения
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Микроэкологическая и ассоциативная структура кишечного биоценоза детей с функциональными нарушениями пищеварения

机译:功能性消化系统疾病患儿肠道生物群落学的微生态学和相关结构

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摘要

The article is devoted to one of actual problems of gastroenterology - study of microbiocenosis of gastrointestinal tract in functional disorders. Functional gastrointestinal disorders (FGID) or minimal dysfunctions of digestion are frequent in the first months of child's life and provoke anxiety both in parents and in pediatricians. Aim: to explore the microbial landscape and the associative structure of the microbiota of the large intestine in children with functional disorders of the gastrointestinal tract. Subjects and methods: Intestinal microbiota composition of 225 children with functional gastrointestinal disorders and 100 healthy children was studied using bacteriological method. Results. The 88.4 % frequency of detection of intestinal eubiosis disorders is discussed. Information is provided on the species composition of the major opportunistic organisms that inhabit this biotope. According to the results, decrease of bifidobacteria amount in structure of large intestine microbiota increases rate of detection of opportunistic microorganisms - predominantly, Klebsiella genus bacteria and Staphylococcus aureus. The intestinal microbial community is dominated by multicomponent transient association. The frequency of detection of pathogenic Staphylococcus in children under one year is discussed in detail. Conclusions. A distinctive feature of the intestinal biocenosis microecological status is significantly greater spread of enterococci than in healthy children, which can be a risk for the emergence of strains with the presence of a number of pathogenecity factors that cause infectious processes.
机译:这篇文章致力于胃肠病学的实际问题之一-功能障碍中胃肠道微生物菌群的研究。功能性胃肠道疾病(FGID)或最小的消化功能障碍在孩子出生的头几个月中很常见,并且在父母和儿科医生中都引起焦虑。目的:探讨胃肠道功能性疾病患儿的大肠微生物群及其相关结构。研究对象和方法:采用细菌学方法研究了225例功能性胃肠疾病的儿童和100名健康儿童的肠道菌群组成。结果。讨论了88.4%的肠道优生病检出率。提供了有关居住在该生物群落中的主要机会生物的物种组成的信息。根据结果​​,大肠微生物群结构中双歧杆菌数量的减少会增加机会性微生物(主要是克雷伯菌属细菌和金黄色葡萄球菌)的检出率。肠道微生物群落以多组分瞬时缔合为主。详细讨论了一年以下儿童中病原性葡萄球菌的检出频率。结论。肠道生物群落微生态状态的一个显着特征是肠球菌的传播比健康儿童大得多,这可能是由于存在许多引起感染过程的致病因素而导致菌株出现的风险。
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