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Digestive disorders and Intestinal microbiota

机译:消化系统疾病和肠道菌群

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In the last decade, a barge body of scientific literature has suggested that specific alterations of the gut microbiota may be associated with ther development and clinical course of several gastrointestinal diseases, including irritable bowel syndrome, inflammatory bowel disease, celiac disease, gastrointestinal cancer and Clostridium difficile infection. These alterations are often referred to as “dysbiosis”, a generic term designing reduction of gut microbiota biodiversity and alterations in its composition. Here, we provide a synthetic overview of the key concepts on the relationship between intestinal microbiota and gastrointestinal diseases, focusing on the translation of these concepts into clinical practice.
机译:在过去的十年中,一组驳斥科学文献的研究表明,肠道菌群的特定改变可能与几种胃肠道疾病的发展和临床过程有关,这些疾病包括肠易激综合症,炎症性肠病,腹腔疾病,胃肠道癌和梭状芽胞杆菌难感染。这些改变通常被称为“营养不良”,这是一个设计术语,旨在减少肠道微生物群的生物多样性及其组成的改变。在这里,我们提供了有关肠道菌群与胃肠道疾病之间关系的关键概念的综合概述,重点是将这些概念转化为临床实践。

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