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Efficacy of Multi-Detector Computed Tomography for the Diagnosis of Medullary Sponge Kidney

机译:多层螺旋CT对海绵状肾的诊断价值

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Objective: To expand the diagnostic armamentarium for medullary sponge kidney (MSK), we evaluate the use of high-resolution multidetector computed tomography (MDCT) for MSK diagnosis and compare to the standard intravenous urography (IVU). Despite a significant prevalence amongst stone formers, diagnosis of this well described condition has declined. IVU, the gold standard in MSK diagnosis, has largely been replaced by CT, which has previously been shown unable to demonstrate signs of MSK. Methods and Materials: Patients with known history of MSK based on IVU underwent limited MDCT urogram. Control group patients, without MSK, also had MDCT urograms performed for other clinically indicated conditions. Studies were scored by board-certified radiologists on a 0-2 scale based on the likelihood of MSK. IVU studies, when available, were similarly graded. Results: MDCT was diagnostic of MSK in 9 out of the 10 patients with known history of MSK. No false positives were present in our series. The one case of MSK not detected on MDCT was graded as a “1” on its respective IVU. Sensitivity and specificity were 90 and 100%, respectively, when compared with IVU. Conclusion: Concordance with IVU findings, despite a small reduction in sensitivity, indicates MDCT to be a suitable, and more readily available replacement for IVU in the diagnosis of MSK.
机译:目的:为扩大海绵状海绵肾(MSK)的诊断装备,我们评估了高分辨率多探测器计算机断层扫描(MDCT)在MSK诊断中的应用,并与标准的静脉泌尿造影(IVU)进行了比较。尽管在结石形成者中患病率很高,但对这种描述良好的疾病的诊断已经下降。 IVU是MSK诊断的黄金标准,在很大程度上已被CT取代,CT先前已显示无法证明MSK的迹象。方法和材料:已知基于IVU的MSK病史的患者接受了有限的MDCT尿路造影。没有MSK的对照组患者也针对其他临床适应症进行了MDCT尿路造影。由董事会认证的放射科医生根据MSK的可能性以0-2评分对研究进行评分。 IVU研究(如果可用)具有类似的等级。结果:在已知MSK病史的10例患者中,有9例MDCT诊断为MSK。在我们的系列中没有假阳性。在MDCT上未检测到的一例MSK在其相应的IVU中被评为“ 1”。与IVU相比,敏感性和特异性分别为90%和100%。结论:尽管敏感性降低了一点,但与IVU的发现相一致,表明MDCT是诊断MSK的合适且更容易获得的IVU替代品。

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