Effect of Different Crown Materials on the InterLeukin-One Beta Content of Gingival Crevicular Fluid in Endodontically Treated Molars: An Original Research

摘要

Introduction Crown materials used in fixed prosthodontics come into close and prolonged contact with the gingiva. Objective The purpose of this study was to evaluate the effect of different crown materials on the interleukin-one beta (IL-1β) content of the gingival crevicular fluid and to study which crown material causes the highest inflammation on the marginal gingiva on a biochemical basis. Materials and Methods Twenty patients with single endodontically treated tooth were examined. Contralateral teeth were taken as controls. The crown materials in contact with the marginal gingiva were divided into three groups: Group 1- metal, Group2- ceramic, Group 3-zirconia. The collected data were analyzed with International Bibliography of the Social Sciences (IBSS). Statistical Package for the Social Sciences (SPSS) Statistics software 23.0 (IBM Corp, Armonk, New York). All assay procedures were carried out and the results of the collected samples were calculated using the ELISA-AIDsupTM/sup technique. Results Multiple comparisons using one-way analysis of variance (ANOVA) between the materials on day?zero, 45supth?/supand 90supth/sup day was highly significant with p=0.0005. Pairwise comparison using Tukey’s honest significant difference (HSD) posthoc test was also highly statistically significant with p= 0.0005 except for ceramic & zirconia which were significant at p=0.04 on the 90supth/sup day. Multiple comparison using repeated measure of ANOVA with Bonferroni correction between day zero, 45supth/sup and 90supth/sup day was found to be statistically significant only for zirconia (p=0.002). Conclusion This study was conducted to evaluate the effect of different crown materials on the amount of marginal gingival inflammation by measuring the IL-1β content in gingival crevicular fluid (GCF). At the end of the three-month analysis, it was seen that the zirconia crowns exhibited the least marginal gingival inflammation.