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Non-Clinical Models for Neurodegenerative Diseases: Therapeutic Approach and Drug Validation in Animal Models

机译:神经退行性疾病的非临床模型:在动物模型中的治疗方法和药物验证

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In 2016, 19.8% of the Cuban population was aged 60 or over. As a result, age-associated degenerative diseases and other diseases have become priority targets from a prophylactic, diagnostic and therapeutic perspective. As a result, the Cuban biomedical scientific community has addressed its basic, preclinical and epidemiological research in order to rise up to the challenge. A firm step in this direction has been the international congress ?¢????State of the art in non-clinical models for neurodegenerative diseases?¢???? which has brought together preclinical and clinical researchers, technicians and regulatory staff members from different countries to review the state of the art in neurodegenerations, find unifying ideas, objectives and collaborations or partnership. The objective is to expose the perspectives of new biotechnological products from Cuba and other countries from the diagnostic, therapeutic and neuroprotective point of view. It is crucial, therefore, that the irreplaceable role of laboratory animals in achieving these objectives is understood but they must be used in rational, adequate and ethical manner. We expose the current development trends in this field, being of common interest to the work directed to the search for potential drugs, diagnostic tools and the promotion of changes in lifestyle as a preventive projection.
机译:2016年,古巴人口中19.8%的年龄在60岁以上。结果,从预防,诊断和治疗的角度来看,与年龄有关的退行性疾病和其他疾病已成为优先目标。结果,古巴生物医学科学界已经对其基础,临床前和流行病学研究进行了研究,以应对挑战。国际大会已朝着这个方向迈出了坚实的一步-非神经退行性疾病的非临床模型中的最新技术水平。来自不同国家的临床前和临床研究人员,技术人员和监管人员汇聚一堂,回顾了神经退行性疾病的最新发展,寻找统一的想法,目标以及合作或伙伴关系。目的是从诊断,治疗和神经保护的角度揭示古巴和其他国家的新生物技术产品的观点。因此,至关重要的是要了解实验动物在实现这些目标中的不可替代的作用,但必须以合理,适当和符合道德的方式使用它们。我们揭示了该领域的当前发展趋势,这与旨在寻找潜在药物,诊断工具和促进生活方式改变的预防工作的共同兴趣。

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