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Computer simulation of thromboexclusion of the complete aorta in the treatment of chronic type B aneurysm

机译:完全血栓排除血栓治疗慢性B型动脉瘤的计算机模拟

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The purpose of this computational study was to examine the hemodynamic parameters of the velocity fields, shear stress, pressure and drag force field in the complex aorta system, based on a case of type B aortic dissection. The extra-anatomic reconstruction of the complete aorta and bipolar exclusion of the aneurysm was investigated by computational fluid dynamics. Three different cases of the same patient were analyzed: the existing preoperative condition and two alternative surgical treatment options, cases A and B, involving different distal aorto-aortic anastomosis sites. The three-dimensional Navier-Stokes equations and the continuity equation were solved with an unsteady stabilized finite element method. The aorta and large tube graft geometries were reconstructed based on CT angiography images to generate a patient-specific 3D finite element mesh. The computed results showed velocity profiles with smaller intensity in the aorta than in the graft tube in the postoperative case. The shear stress distribution showed low zones around 0.5?Pa in the aneurysm part of the aorta for all three cases. Pressure distribution and, particularly, drag force had much higher values in the preoperative aneurysm zones (7.37?N) than postoperatively (2.45?N), which provides strong evidence of the hemodynamic and biomechanical benefits of this type of intervention in this specific patient. After assessing the outcome obtained with each of the two alternatives A and B, for which we found no significant difference, it was decided to use option A to treat the patient. In summary, computational studies could complement surgical preoperative risk assessment and provide significant insight into the benefits of different treatment alternatives.
机译:这项计算研究的目的是基于B型主动脉夹层的情况,检查复杂主动脉系统中速度场,切应力,压力和阻力场的血液动力学参数。通过计算流体动力学研究了完整主动脉的解剖外重建和动脉的双极排斥。分析了同一患者的三例不同病例:术前的现有状况和两种可选的手术治疗方案,病例A和B,涉及不同的远端主动脉主动脉吻合部位。用非稳态稳定有限元方法求解了三维Navier-Stokes方程和连续性方程。根据CT血管造影图像重建主动脉和大管移植物的几何形状,以生成患者特定的3D有限元网格。计算结果表明,在术后情况下,主动脉内的速度分布比移植管内的强度小。在所有三种情况下,主动脉瘤部分的切应力分布均显示在0.5?Pa附近的低区。术前动脉瘤区域的压力分布(特别是阻力)(7.37?N)比术后(2.45?N)高得多,这为此类患者提供了这种干预措施对血液动力学和生物力学益处的有力证据。在评估了我们发现无明显差异的两个备选方案A和B各自获得的结果后,决定使用方案A来治疗患者。总之,计算研究可以补充手术前的风险评估,并对不同治疗方案的益处提供重要的见识。

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