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A novel method for evaluating sun visible light protection factor and pigmentation protection factor of sunscreens

机译:一种评估防晒剂的阳光可见光保护因子和色素沉着保护因子的新方法

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Introduction: The role of visible light (VL) in the process of skin pigmentation by solar radiation has been demonstrated. Sunscreens with the presence of pigments, particularly iron oxide (IO), have a greater protective effect against VL and are, therefore, highly recommended for prevention and treatment of hyperpigmentation disorders. This study aimed to evaluate 33 sunscreen formulations, and through spectrophotometric measurements, proposes new methods to evaluate the VL protection factor and the pigmentation protection factor. Methods: 33 sunscreen formulations marketed in Brazil were evaluated, including 17 products containing pigments and 16 products with no pigments. Spectrophotometric measurements were taken to determine solar VL protection factor and the pigmentation protection factor, based on the absorption curve of the product, the pigmentation action spectrum and sun spectrum. Results: Sunscreen with pigments presented a higher solar VL protection factor and pigmentation protection factor compared to products without pigment. The statistical analysis showed a strong correlation between the solar VL protection factor and the integral of the absorption curve in the VL range and the transmittance reduction (%) in the same range. The correlation between the VL protection factor and the pigmentation protection factor was also demonstrated. Conclusion: The VL protection factor and the pigmentation protection factor showed to be adequate metrics to estimate the effectiveness of sunscreens in the prevention of the pigmentary effect of solar VL and the pigmentary effect of the complete spectrum of immediate pigmentation.
机译:简介:已经证明了可见光(VL)在太阳辐射引起的皮肤色素沉着过程中的作用。含有颜料,尤其是氧化铁(IO)的防晒霜对VL具有更大的保护作用,因此,强烈建议用于预防和治疗色素沉着过多的疾病。这项研究旨在评估33种防晒霜配方,并通过分光光度法测量,提出了评估VL保护因子和色素沉着保护因子的新方法。方法:评估了在巴西销售的33种防晒霜配方,包括17种含有色素的产品和16种不含色素的产品。根据产品的吸收曲线,色素沉着作用谱和太阳光谱,采用分光光度法测定日照VL保护因子和色素沉着保护因子。结果:与不含颜料的产品相比,含颜料的防晒霜具有更高的日光VL保护因子和色素沉着保护因子。统计分析表明,太阳VL保护因子与VL范围内的吸收曲线的积分与相同范围内的透射率降低(%)之间具有很强的相关性。还证明了VL保护因子和色素沉着保护因子之间的相关性。结论:VL保护因子和色素沉着保护因子是评估防晒霜在预防太阳VL色素效应和立即色素沉着整个光谱中的色素效应的有效性的充分指标。

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