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Bilateral lid/brow elevation procedure for severe ptosis in Kearns-Sayre syndrome, a mitochondrial?cytopathy

机译:双侧眼睑/眉毛抬高手术可治疗线粒体细胞病的Kearns-Sayre综合征

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Background: The purpose of this work was to determine the effectiveness and possible complications encountered with bilateral fascia lata lid suspension used to correct blepharoptosis in patients with Kearns-Sayre syndrome.Methods: This was a retrospective study of seven patients with Kearns-Sayre syndrome who had a minimum of 1 year of follow-up. A bilateral fascia lata sling was used to correct the ptosis. Preoperative and postoperative measurements of the vertical lid fissure width (VFW) and marginal reflex distance (MRD) were performed. The Student’s t-test was used to analyze the results.Results: The mean preoperative VFW and MRD measurements were 4±2.45 mm and 0.14±0.92?mm, respectively. The mean postoperative VFW and MRD measurements were 7.71±1.85 mm, and 2.86±1.69 mm, respectively. All preoperative and postoperative values were considered to be statistically significant (P<0.01). Adequate elevation of the lids was obtained in all patients, both functionally and aesthetically. All of the patients showed a mild symmetric postoperative inferior version lagophthalmos, and one patient developed corneal ulceration and scarring due to corneal exposure and a weak Bell’s phenomenon.Conclusion: The surgical technique described to correct the blepharoptosis found in patients with Kearns-Sayre syndrome was found to be efficient and relatively safe. The correction should be conservative to decrease the risk of postoperative corneal damage that occurred in one patient.
机译:背景:这项工作的目的是确定用于校正Kearns-Sayre综合征患者的双眼筋膜炎的双侧筋膜Lata盖悬吊术的有效性和可能出现的并发症。方法:这项回顾性研究对7名Kearns-Sayre综合征患者进行了回顾性研究。至少进行了1年的随访。使用双侧筋膜带吊带矫正上睑。术前和术后测量垂直眼睑裂隙宽度(VFW)和边缘反射距离(MRD)。结果:术前VFW和MRD的平均测量值分别为4±2.45 mm和0.14±0.92?mm。术后VFW和MRD的平均测量值分别为7.71±1.85 mm和2.86±1.69 mm。所有术前和术后值均被认为具有统计学意义(P <0.01)。在功能和美学上,所有患者均获得了足够的眼睑盖度。所有患者均表现为轻度对称的术后下眼角膜炎,其中一名患者由于角膜暴露和贝尔现象较弱而出现角膜溃疡和瘢痕形成。结论:描述的纠正Kearns-Sayre综合征患者眼睑睑下垂病的手术技术是被认为是高效且相对安全的。校正应保守,以减少一名患者发生术后角膜损伤的风险。

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