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Quetiapine Induced Autoimmune Hemolytic Anemia in a Child Patient: A Case Report

机译:喹硫平引起的一名儿童患者自身免疫性溶血性贫血:一例报告

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Autoimmune hemolytic anemia is a disease characterized with destruction of erythrocytes as a result of antibody produce against patient’s own erythrocytes and anemia. Autoimmune hemolytic anemia can be roughly stratified into two groups according to serological features and secondary causes including drugs induced hemolytic anemia. Drugs induced autoimmune hemolytic anemia is very rare in pediatric patients. Even though hematological side effects such as leucopenia, agranulocytosis, eosinophilia, thrombocytopenic purpura and aplastic anemia might occur due to psychotropic drug use; to the best of our knowledge there is no autoimmune hemolytic anemia case due to quetiapine, an atypical antipsychotics, in literature. We hereby describe the first child case of autoimmune hemolytic anemia during quetiapine treatment.We also are pointing out that one should keep in mind serious hematological side effects with atypical antipsychotic drug use with this case report.
机译:自身免疫性溶血性贫血是一种以患者自身的红细胞和贫血产生抗体的结果为特征的红细胞破坏的疾病。根据血清学特征和包括药物引起的溶血性贫血在内的次要原因,自身免疫性溶血性贫血可以大致分为两类。药物引起的自身免疫性溶血性贫血在小儿患者中非常罕见。即使由于使用药物而可能发生血液学方面的副作用,如白细胞减少症,粒细胞缺乏症,嗜酸性粒细胞增多症,血小板减少性紫癜和再生障碍性贫血;据我们所知,目前尚无非典型抗精神病药物喹硫平引起的自身免疫性溶血性贫血病例。我们在此描述喹硫平治疗期间首例自身免疫性溶血性贫血的儿童病例。我们还指出,该病例报告应牢记非典型抗精神病药物的严重血液学副作用。

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