Clinical outcomes of wavefront-guided laser in situ keratomileusis to treat moderate-to-high astigmatism

摘要

Purpose: The purpose of this study was to evaluate the refractive and visual outcomes of wavefront-guided laser in situ keratomileusis (LASIK) in eyes with myopic astigmatism and cylindrical component ≥2.0 diopter (D).Methods: In this retrospective study, 611 eyes that underwent LASIK for simple or compound myopic astigmatism were analyzed. Preoperative refractive cylinder ranged from -2.00?D to -6.00?D (mean -2.76±0.81?D), and the sphere was between 0.00?D and -9.75?D (mean -2.79±2.32?D). Predictability, visual outcomes, and vector analysis of changes in refractive astigmatism were evaluated.Results: At 3?months after LASIK, 83.8% of eyes had uncorrected distance visual acuity of 20/20 or better, 90.3% had manifest spherical equivalent within ±0.50?D, and 79.1% had residual refractive cylinder within ±0.50?D of intended correction. The mean correction ratio for refractive cylinder was 0.92±0.14, the mean error of angle was -0.45°±2.99°, and the mean error vector was 0.37±0.38?D. A statistically significant correlation was found between the error of magnitude (arithmetic difference in the magnitudes between surgically induced refractive correction and intended refractive correction) and the intended refractive correction (r=0.26, P<0.01).Conclusion: Wavefront-guided LASIK for the correction of myopic astigmatism is safe, effective, and predictable.