首页> 外文期刊>Case Reports in Ophthalmology >Changes in the Retinal Vascular Network Morphology (Diameter and Tortuosity) after Administration of Intravitreal Bevacizumab in a Patient with Ischaemic Branch Retinal Vein Occlusion
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Changes in the Retinal Vascular Network Morphology (Diameter and Tortuosity) after Administration of Intravitreal Bevacizumab in a Patient with Ischaemic Branch Retinal Vein Occlusion

机译:缺血性视网膜视网膜静脉阻塞患者玻璃体内贝伐单抗给药后视网膜血管网络形态(直径和曲折度)的变化

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We report a case of transient reduction in the diameter and tortuosity of an occluded vessel after intravitreal administration of 1.25 mg (0.05 ml) bevacizumab in a patient with ischaemic branch retinal vein occlusion. A 64-year-old hypertensive female presented with chief complaints of reduced vision in her right eye for 3 months. Her vision in the right eye was evaluated as counting fingers at 2 m. Fundus examination revealed superotemporal branch retinal vein occlusion. On fluorescein angiography, in the superotemporal quadrant, there was hyperfluorescence that increased in size and intensity in the late phase, suggestive of a leaking neovascular frond. In addition, there was capillary non-perfusion in the adjacent area. The patient was administered 1.25 mg (0.05 ml) of bevacizumab intravitreally in her right eye, under all aseptic precautions. After 1 week, her right eye fundus showed regression of neovascularisation. Fluorescein angiography also demonstrated regression of neovascularisation in addition to a decrease in the diameter and tortuosity of the retinal vessel.
机译:我们报告了在缺血性视网膜分支静脉阻塞患者中玻璃体内给药1.25 mg(0.05 ml)贝伐单抗后玻璃体直径和曲折性短暂降低的情况。一名64岁的高血压女性患者主诉其右眼视力下降3个月。通过在2 m处计数手指来评估她在右眼中的视力。眼底检查显示颞上分支视网膜静脉闭塞。在荧光素血管造影术中,在颞上象限中,在末期出现过度荧光,其大小和强度增加,提示新血管叶漏出。此外,在相邻区域没有毛细血管灌注。在所有无菌预防措施下,患者右眼玻璃体内给予1.25 mg(0.05 ml)贝伐单抗。 1周后,她的右眼眼底显示出新生血管的消退。荧光素血管造影还显示出新生血管的消退,以及视网膜血管直径和曲折度的降低。

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