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Spinal Intramedullary Metastasis of Breast Cancer

机译:乳腺癌的脊髓髓内转移

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Objective.Breast cancer accounts for approximately one-third of all cancers in females. Approximately 8.5 % of all central nervous system metastases are located in the spinal cord. These patients have rapidly progressing neurological deficits and require immediate examination. The aim of surgery is decompression of neural tissue and histological evaluation of the tumor. In this paper, we present a case of breast cancer metastasis in thoracic spinal intramedullary area which had been partially excised and then given adjuvant radiotherapy.Case.A 43-year-old female patient with breast cancer for 8 years was admitted to our hospital with complaints of weakness in both legs. Eight years ago, she received chemotherapy and radiotherapy. On her neurological examination, she had paraparesis (left lower extremity: 2/5, right lower extremity: 3/5) and urinary incontinence. Spinal MRI revealed a gadolinium enhancing intramedullary lesion. Pathologic examination of the lesion was consistent with breast carcinoma metastasis. The patient has been taken into radiotherapy.Conclusion.Spinal intramedullary metastasis of breast cancer is an extremely rare situation, but it has a high morbidity and mortality rate. Microsurgical resection is necessary for preservation or amelioration of neurological state and also for increased life expectancy and quality.
机译:目的:乳腺癌约占女性所有癌症的三分之一。所有中枢神经系统转移中约有8.5%位于脊髓中。这些患者神经疾病迅速发展,需要立即检查。手术的目的是神经组织减压和肿瘤的组织学评估。本文介绍了一例经胸椎切开的髓内区域的乳腺癌转移病例,并进行了辅助放疗。病例:一名43岁的女性乳腺癌患者,有8年的时间被我院收治。抱怨双腿无力。八年前,她接受了化学疗法和放射疗法。在神经系统检查中,她患有轻瘫(左下肢:2/5,右下肢:3/5)和尿失禁。脊柱MRI显示revealed增强了髓内病变。病变的病理检查与乳腺癌转移一致。该患者已接受放射治疗。结论。乳腺癌的脊髓髓内转移是一种极为罕见的情况,但其发病率和死亡率很高。显微外科切除术对于保存或改善神经系统状态以及延长预期寿命和质量是必要的。

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