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Primary Intimal (Spindle Cell) Sarcoma of the Heart: A Case Report and Review of the Literature

机译:心脏原发性内膜(纺锤状细胞)肉瘤:一例报道并文献复习

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Intimal (spindle cell) sarcomas of the left atrium are extremely rare primary cardiac tumours with three cases reported (Li et al. (2013), Cho et al. (2006), and Modi et al. (2009)). We present a 69-year-old man who first came to medical attention after experiencing abdominal discomfort. He had a 30 lb weight loss apparently due to dieting. He denied any other constitutional symptoms. His symptoms persisted despite a course of antibiotics for presumed diverticulitis. Laboratory values were within normal limits, though the haemoglobin was 131 g/L (normal: 140–180). Subsequent abdominal computed tomography (CT) scan revealed an abdominal wall mass and intracardiac lesion; the cardiac mass was further characterized by transesophageal echo (TEE), magnetic resonance imaging (MRI), and dedicated cardiac CT. TEE revealed a mass attached to the posterolateral wall of the left atrium above the mitral annulus, and the cardiac CT and MRI confirmed the TEE findings. The patient underwent extensive surgical resection and repair of the left side of the heart. Postoperatively, he developed acute renal failure requiring dialysis and reintubation for volume overload. He became acutely hypotensive, developed multiorgan failure, and succumbed to his illness. Histopathologic examination of the left atrial mass showed an intimal sarcoma.
机译:左心房的内膜(纺锤状细胞)肉瘤是极为罕见的原发性心脏肿瘤,已有三例报道(Li等人(2013),Cho等人(2006)和Modi等人(2009))。我们介绍了一个69岁的男子,他在经历腹部不适后首次就医。由于节食,他的体重减轻了30磅。他否认有任何其他体质症状。尽管为推测的憩室炎使用了抗生素,他的症状仍然持续。尽管血红蛋白为131μg/ L(正常值:140-180),实验室值仍在正常范围内。随后的腹部计算机断层扫描(CT)扫描显示腹部壁肿块和心内病变。经食道回声(TEE),磁共振成像(MRI)和专用心脏CT进一步表征了心脏质量。 TEE显示二尖瓣环上方左心房后外侧壁附着有肿块,心脏CT和MRI证实了TEE的发现。该患者接受了广泛的外科手术切除并修复了心脏的左侧。术后,他发展为急性肾功能衰竭,需要透析和重新插管以应对容量超负荷。他患有急性降压症,发展为多器官衰竭,并死于自己的病。左心房肿块的组织病理学检查显示内膜肉瘤。

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