Initiation of Noninvasive Ventilation for Sleep Related Hypoventilation Disorders: Advanced Modes and Devices

摘要

Prevalent alveolar and sleep related hypoventilation disorders include patients with COPD presenting with acute-on-chronic hypercapnic respiratory failure, overlap syndrome (COPD plus OSA), obesity hypoventilation syndrome (OHS), and progressive restrictive pulmonary disorders, such as thoracic cage abnormalities and neuromuscular disease (NMD). Careful selection of NIV mode and settings should be based on the patient’s distinctive needs and level of acute illness. This review focuses on providing a practical approach to NIV in prevalent stable sleep-related alveolar hypoventilation syndromes, both in non-ICU hospital settings and at home, with emphasis on customizing NIV settings to the patient’s unique physiology of respiratory failure.Noninvasive ventilation (NIV) is used widely in hospitalized patients with COPD presenting with acute-on-chronic hypercapnic respiratory failure,