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Early‐Stage Incorporation Strategy for Regioselective Labeling of Peptides using the 2‐Cyanobenzothiazole/ 1,2‐Aminothiol Bioorthogonal Click Reaction

机译:使用2-氰基苯并噻唑/ 1,2-氨基硫醇生物正交点击反应对肽进行区域选择性标记的早期掺入策略

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Invited for this month's cover picture is the group of Dr. Yann Seimbille at the Life Sciences Division at TRIUMF (Canada). The cover picture shows how a simple and innovative methodology based on the bioorthogonal click reaction between 2‐cyanobenzothiazole and 1,2‐aminothiol has been elaborated to facilitate the labeling of peptide biovectors. Read the full text of their Communication at 10.1002/open.201700191 . “A simple and innovative methodology based on the bioorthogonal click reaction between 2‐cyanobenzothiazole and 1,2‐aminothiol is elaborated to facilitate the labeling of peptide biovectors. This strategy is anticipated to be a useful tool in the development of new peptide‐based imaging probes for biomedical applications …” Find out more about the story behind the front cover research at 10.1002/open.201700191 .
机译:受邀参加本月封面照片的是TRIUMF(加拿大)生命科学部门的Yann Seimbille博士。封面图片显示了如何基于2-氰基苯并噻唑和1,2-氨基硫醇之间生物正交点击反应的简单创新方法,以促进肽生物载体的标记。阅读其通讯全文,网址为10.1002 / open.201700191。 “基于2-氰基苯并噻唑和1,2-氨基硫醇之间的生物正交点击反应的简单创新方法,旨在促进肽生物载体的标记。有望在开发用于生物医学的新的基于肽的成像探针时使用该策略。……在10.1002 / open.201700191上找到有关封面研究背后故事的更多信息。

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