Ultrasound Assisted Synthesis of Diethyl-2,2?￠????-Thiodiacetate with2-Bromoethylacetate Under a New Polymer-Supported Phase-TransferCatalyst in Solid-Liquid Condition

摘要

In this work, a new polystyrene-bound single-onium phase-transfer catalyst was synthesized, and their catalytic activities were investigated in the synthesis of diethyl-2,2’-thio diacetate derivatives of thioether. The new insoluble polymer anchored mono-site phase-transfer catalyst showed significant high catalytic activity as compared to soluble single site phase-transfer catalysts. The comparative kinetic investigation reveals that the diethyl-2,2’-thio diacetate of ethyl-2-bromoacetate is faster than sodium sulfide in the presence of the new catalyst. This catalyst can be used several times with consistent catalytic activity. Experimental observations support an interfacial-type mechanism.