Activating transcription factor 3 is downregulated in hepatocellular carcinoma and functions as a tumor suppressor by regulating cyclin D1

Zheng-xia Wang; Si-neng Yin; Gang Tian; Xian-lin Chen

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Activating transcription factor 3 is downregulated in hepatocellular carcinoma and functions as a tumor suppressor by regulating cyclin D1

机译：在肝细胞癌中激活转录因子3被下调，并通过调节细胞周期蛋白D1发挥抑癌作用

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Objectives To investigate the expression as well as biological roles of activating transcription factor 3 (ATF3) in human hepatocellular carcinoma (HCC) cells.

机译：目的探讨活化转录因子3（ATF3）在人肝细胞癌（HCC）细胞中的表达及其生物学作用。

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《Central European Journal of Biology》 |2016年第1期|共5页
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Zheng-xia Wang; Si-neng Yin; Gang Tian; Xian-lin Chen;
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中图分类生物科学;
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入库时间 2022-08-18 06:25:04

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1. Degradative autophagy selectively regulates CCND1 (cyclin D1) and MIR224, two oncogenic factors involved in hepatocellular carcinoma tumorigenesis [J] . Wu Shan-Ying, Lan Sheng-Hui, Liu Hsiao-Sheng Autophagy . 2019,第4期

机译：降解性自噬选择地调节CCND1（细胞周期蛋白D1）和MiR224，两个致癌因子患者患有肝细胞癌肿瘤瘤的癌症
2. p53 and miR‐210 regulated NeuroD2, a neuronal basic helix–loop–helix transcription factor, is downregulated in glioblastoma patients and functions as a tumor suppressor under hypoxic microenvironment [J] . Agrawal Rahul, Garg Ankita, Benny Malgulwar Prit, International Journal of Cancer =: Journal International du Cancer . 2018,第9期

机译：P53和miR-210受调节的神经元，一种神经元碱性螺旋环 - 螺旋转录因子在胶质母细胞瘤患者中下调，并用作缺氧微环境下的肿瘤抑制剂
3. BDH2 is downregulated in hepatocellular carcinoma and acts as a tumor suppressor regulating cell apoptosis and autophagy [J] . Hao Liang, Zhiyong Xiong, Ruixi Li, Journal of Cancer . 2019,第16期

机译：BDH2在肝细胞癌中下调，并作为肿瘤抑制因子调节细胞凋亡和自噬
4. ACTIVATING TRANSCRIPTION FACTOR 4 INCREASE CHEMORESISTANCE OF HUMAN HEPATOCELLULAR CARCINOMA [C] . Zhuhong Zhang, Na Li, Dan Lv, 2011 Asia-Pacific Conference of tumor biology and medicine . 2011

机译：激活转录因子4提高人肝细胞癌的化学耐药性
5. Walleye retroviral cyclins phosphorylate pRb tumor suppressor and the walleye dermal sarcoma retrovirus cyclin and G2/M cyclins repress transcription of p14ARF tumor suppressor through interaction with TBX2, possibly contributing to tumorigenesis. [D] . Kim, Sang-Woo. 2004

机译：角膜白斑逆转录病毒细胞周期蛋白使pRb肿瘤抑制蛋白磷酸化，而角膜皮肉瘤逆转录病毒细胞周期蛋白和G2 / M细胞周期蛋白通过与TBX2相互作用抑制p14ARF肿瘤抑制因子的转录，可能有助于肿瘤发生。
6. Degradative autophagy selectively regulates CCND1 (cyclin D1) and MIR224 two oncogenic factors involved in hepatocellular carcinoma tumorigenesis [O] . Shan-Ying Wu, Sheng-Hui Lan, Hsiao-Sheng Liu 2019

机译：降解自噬选择性调节CCND1（cyclin D1）和MIR224这是两个参与肝细胞癌发生的致癌因素
7. Activating transcription factor 3 is downregulated in hepatocellular carcinoma and functions as a tumor suppressor by regulating cyclin D1 [O] . Wang Zheng-xia, Yin Si-neng, Tian Gang, 2016

机译：激活转录因子3在肝细胞癌中下调并且通过调节细胞周期蛋白D1起到肿瘤抑制剂的作用

Activating transcription factor 3 is downregulated in hepatocellular carcinoma and functions as a tumor suppressor by regulating cyclin D1

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