首页> 外文期刊>Cell stress & chaperones >Cold stress induces antioxidants and Hsps in chicken immune organs
【24h】

Cold stress induces antioxidants and Hsps in chicken immune organs

机译:冷应激会在鸡的免疫器官中诱导抗氧化剂和Hsps

获取原文
           

摘要

The aim of this study was to investigate the effects of cold stress on oxidative indexes, immune function, and the expression levels of heat shock protein (Hsp90, Hsp70, Hsp60, Hsp40, and Hsp27) in immune organs of chickens. Two hundred forty 15-day-old male chickens were randomly divided into 12 groups and kept under the temperature of (12?±?1)?°C for acute and chronic cold stress. There were one control group and five treatment groups for acute cold stress and three control groups and three treatment groups for chronic cold stress. The results showed that cold stress influence the activities of antioxidant enzymes in the immune organs. The activities of SOD and GSH-Px were first increased then decreased, and activity of total antioxidation capacity (T-AOC) was significantly decreased (P?
机译:这项研究的目的是研究冷应激对鸡免疫器官中氧化指标,免疫功能以及热休克蛋白(Hsp90,Hsp70,Hsp60,Hsp40和Hsp27)表达水平的影响。将250只15天大的雄性鸡随机分为12组,并在(12±±1)°C的温度下处理急性和慢性冷应激。急性冷应激有一个对照组和五个治疗组,慢性冷应激有三个对照组和三个治疗组。结果表明,冷应激影响免疫器官中抗氧化酶的活性。雏鸡急性冷应激时,SOD和GSH-Px活性先升高后降低,总抗氧化能力(T-AOC)明显降低(P≤0.05)。然而,在这些组织的慢性冷应激下,T-AOC活性显着增加(P≤0.05)。冷应激诱导鸡免疫器官中丙二醛(MDA)含量升高。此外,冷应激组细胞因子含量增加。作为一种保护因子,在两个冷应激组中,Hsps的表达水平均显着增加(P≤0.05)。这些结果表明冷应激在三个组织中诱导氧化应激并影响雏鸡的免疫功能。 Hsps(Hsp90,Hsp70,Hsp60,Hsp40和Hsp27)的高表达可能在保护免疫器官抵抗冷应激中起作用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号