The Anticancer Activity of the Substituted Pyridone-Annelated Isoindigo (5'-Cl) Involves G0/G1 Cell Cycle Arrest and Inactivation of CDKs in the Promyelocytic Leukemia Cell Line HL-60

Ayman M. Saleh; Ahmad Aljada; Mustafa M. El-Abadelah; Mutasem O. Taha; Salim S. Sabri; Jalal A. Zahra; Mohammad Azhar Aziz

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The Anticancer Activity of the Substituted Pyridone-Annelated Isoindigo (5'-Cl) Involves G0/G1 Cell Cycle Arrest and Inactivation of CDKs in the Promyelocytic Leukemia Cell Line HL-60

机译：取代的吡啶酮-环的异靛蓝（5'-Cl）的抗癌活性涉及早幼粒细胞白血病细胞株HL-60的G0 / G1细胞周期阻滞和CDK的失活。

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《Cellular Physiology and Biochemistry》 |2015年第5期|共15页
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Ayman M. Saleh; Ahmad Aljada; Mustafa M. El-Abadelah; Mutasem O. Taha; Salim S. Sabri; Jalal A. Zahra; Mohammad Azhar Aziz;
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中图分类细胞生物物理学;
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1. A novel adenosine analog, thio-Cl-IB-MECA, induces G0/G1 cell cycle arrest and apoptosis in human promyelocytic leukemia HL-60 cells. [J] . Lee EJ, Min HY, Chung HJ, Biochemical Pharmacology . 2005,第6期

机译：一种新型的腺苷类似物，硫代-Cl-IB-MECA，在人早幼粒细胞白血病HL-60细胞中诱导G0 / G1细胞周期停滞和凋亡。
2. Antiproliferative activity of the isoindigo 5'-Br in HL-60 cells is mediated by apoptosis, dysregulation of mitochondrial functions and arresting cell cycle at G0/G1 phase. [J] . Ayman M Saleh, Mustafa M El-Abadelah, Mohammad Azhar Aziz, Cancer letters . 2015,第2期

机译：靛蓝5'-Br在HL-60细胞中的抗增殖活性是由细胞凋亡，线粒体功能失调和细胞周期阻滞在G0 / G1期介导的。
3. Ethyl acetate fraction of Garcina epunctata induces apoptosis in human promyelocytic cells (HL-60) through the ROS generation and G0/G1 cell cycle arrest: A bioassay-guided approach [J] . Pieme Constant Anatole, Santoh Kumar Guru, Ngamegni Bathelemy, Environmental toxicology and pharmacology . 2013,第3期

机译：藤黄藤的乙酸乙酯级分通过ROS产生和G0 / G1细胞周期停滞诱导人早幼粒细胞（HL-60）的凋亡：一种生物测定指导方法
4. Alteronol Induces Cycle Arrest in Human Promyelocytic Leukemia (HL-60) Cells [C] . Yao Ying, Chen Hongmei, Chen Ji, 5th International Conference on Bioinformatics and Biomedical Engineering . 2011

机译：Alteronol诱导人类早幼粒细胞白血病（HL-60）细胞的周期阻滞。
5. Small molecule modulation of the cell cycle: Discovery of anticancer compounds that induce G1- and M-phase cell cycle arrest and characterization of their modes of action. [D] . Leslie, Benjamin. 2009

机译：细胞周期的小分子调节：诱导G1期和M期细胞周期停滞及其作用方式表征的抗癌化合物的发现。
6. Lp16-PSP a Member of YjgF/YER057c/UK114 Protein Family Induces Apoptosis and p21WAF1/CIP1 Mediated G1 Cell Cycle Arrest in Human Acute Promyelocytic Leukemia (APL) HL-60 Cells [O] . Thomson Patrick Joseph, Warren Chanda, Abdullah Faqeer Mohammad, 2017

机译：Lp16-PSPYjgF / YER057c / UK114蛋白家族的成员诱导人急性早幼粒细胞白血病（APL）HL-60细胞凋亡和p21WAF1 / CIP1介导的G1细胞周期阻滞。
7. The Anticancer Activity of the Substituted Pyridone-Annelated Isoindigo (5'-Cl) Involves G0/G1 Cell Cycle Arrest and Inactivation of CDKs in the Promyelocytic Leukemia Cell Line HL-60 [O] . Ayman M. Saleh, Ahmad Aljada, Mustafa M. El-Abadelah, 2015

机译：取代吡啶酮 - 安定的异靛蓝（5'-Cl）的抗癌活性涉及早幼粒细胞白血病细胞系HL-60中G0 / G1细胞周期阻滞和CDK失活。

The Anticancer Activity of the Substituted Pyridone-Annelated Isoindigo (5'-Cl) Involves G0/G1 Cell Cycle Arrest and Inactivation of CDKs in the Promyelocytic Leukemia Cell Line HL-60

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