Development of Graft-Site Candidiasis in 3 Solid Organ Transplant Recipients from the Same Donor

摘要

Objective: Unusual clinical course Background: Graft-site candidiasis rarely develops in solid organ transplant recipients; however, severe life-threatening com- plications can occur. We report the course of 3 solid organ transplant recipients developing graft-site candidiasis. Case report: All grafts, consisting of 2 kidneys and 1 liver, were procured from a single donor. Patient data were collected from our database. Candida albicans was isolated from a swab taken during multiple-organ recovery. Complications associated with candidiasis occurred in all 3 recipients with preservation of the liver transplant. Both renal transplant re- cipients had vascular complications, eventually resulting in graft nephrectomy and subsequent return to dial- ysis. The patients recovered completely without residual effects of their prior fungal infection. Conclusions: Fungal infections in solid organ transplant recipients are rare. Since the sequelae of these infections are seri- ous and usually pertain to more than 1 recipient at a time, antifungal prophylaxis may be warranted in select donors.