首页> 外国专利> Method for the early detection of breast cancer, lung cancer, pancreatic cancer and colon polyps, growths and cancers as well as other gastrointestinal disease conditions and the preoperative and postoperative monitoring of transplanted organs from the donor and in the recipient and their associated conditions related and unrelated to the organ transplantation

Method for the early detection of breast cancer, lung cancer, pancreatic cancer and colon polyps, growths and cancers as well as other gastrointestinal disease conditions and the preoperative and postoperative monitoring of transplanted organs from the donor and in the recipient and their associated conditions related and unrelated to the organ transplantation

机译:早期检测乳腺癌,肺癌,胰腺癌和结肠息肉,生长和癌症以及其他胃肠道疾病状况的方法以及从供体和受者体内移植器官的术前和术后监测以及与之相关的相关疾病的方法与器官移植无关

摘要

A method for the early diagnosis of breast, lung, pancreatic and colon growths and cancers as well as conditions associated with donor and recipient organ transplants, both before and after transplantation to identify and allow treatment of possible transplanted organ rejection and other disease conditions related and unrelated to the transplantation, compares the gene expression patterns from a patient's peripheral blood monocytes-lymphocyte's gene system with either the similar gene expression patterns of a normal person, or with the similar gene expression patterns of a person known to have the condition being screened for. Differences between the patient's gene expression patterns for particular genes and the normal patterns indicates the presence of the condition with the number of differences indicating the probability of the condition. Similarities between the patient's gene expression patterns for those particular genes and the patterns of a person known to have the condition indicates the presence of the condition with the number of similarities indicating the probability of the condition. For example, particular genes for use in identifying pancreatic cancer are disclosed.
机译:一种在移植前后对乳房,肺,胰腺和结肠生长以及癌症以及与供体和受体器官移植相关的疾病进行早期诊断的方法,以识别并治疗可能的移植器官排斥反应以及与之相关的其他疾病与移植无关,将患者外周血单核细胞-淋巴细胞基因系统的基因表达模式与正常人的相似基因表达模式,或与已知患有该疾病的人的相似基因表达模式进行比较。患者特定基因的基因表达模式与正常模式之间的差异表示疾病的存在,差异的数量表示疾病的可能性。那些特定基因的患者基因表达模式与已知患有该疾病的人的模​​式之间的相似性表明该疾病的存在,而相似性的数量则表明该疾病的可能性。例如,公开了用于鉴定胰腺癌的特定基因。

著录项

  • 公开/公告号US2006088876A1

    专利类型

  • 公开/公告日2006-04-27

    原文格式PDF

  • 申请/专利权人 A. ROBERT BAUER;

    申请/专利号US20050266901

  • 发明设计人 A. ROBERT BAUER;

    申请日2005-11-05

  • 分类号C12Q1/68;

  • 国家 US

  • 入库时间 2022-08-21 21:46:17

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