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Subcorneal Pustular Dermatosis in Childhood: A Case Report and Review of the Literature

机译:儿童角膜下脓疱性皮肤病:一例报道并文献复习

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Subcorneal pustular dermatosis (SCPD, also known as Sneddon-Wilkinson disease) is a rare, benign, chronic, sterile pustular eruption which usually develops in middle-age or elderly women; it is rarely seen in childhood and adolescence. The primary lesions are pea-sized pustules classically described as half-pustular, half-clear flaccid blisters. Histologically the most important feature is a subcorneal accumulation of neutrophils with the absence of spongiosis or acantholysis, although acantholysis may be reported in older lesions. In this paper we present the case of a 7-year-old boy diagnosed with SCPD based on the characteristic clinical and histological features. Dapsone has been successfully used in the treatment of the disease.
机译:角膜下脓疱性皮肤病(SCPD,也称为Sneddon-Wilkinson病)是一种罕见,良性,慢性,无菌性脓疱疹,通常在中年或老年妇女中发展;在儿童和青少年时期很少见。主要病变是豌豆大小的脓疱,传统上称其为半脓疱,半透明的松弛性水疱。从组织学上看,最重要的特征是嗜中性粒细胞在角膜下积聚,而没有海绵状或棘层松解症,尽管在较旧的病变中有棘层松解症的报道。在本文中,我们根据特征性临床和组织学特征介绍了一名7岁男孩被诊断​​患有SCPD的病例。氨苯砜已经成功地用于治疗该疾病。

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