URIC ACID: HIS POSSIBLE ROLE AS ANTIOXIDANT IN HORSES WITH EQUINE INFECTIOUS ANEMIA

摘要

Equine infectious anemia virus (EIAV) is a lentivirus, of the Retrovirus family, with an almost worldwide distribution, infecting equids (4).Uric acid may be a marker of oxidative stress (1) and may have a potential therapeutic role as an antioxidant On the other hand, like other strong reducing substances such as ascorbate, uric acid can also act as a peroxidant particularly at elevated levels. Thus, it is unclear whether elevated levels of uric acid in diseases associated with oxidative stress such as stroke and atherosclerosis are a protective response or a primary cause (5). For example, some researchers propose that hyperuricemia-induced oxidative stress is a cause of metabolic syndrome (5). On the other hand, plasma uric acid levels correlate with longevity in primates and other mammals (2). This is presumably a function of urate's antioxidant properties