New Nickel Metal Complex towards Biomimetic Catecholase Enzyme Oxidation: Synthesis and Kinetics Studies

摘要

Pyrano[2,3-c]pyrazole ligand and their transition metal complex with nickel (NisupII/supMPC) were synthesized and characterization by elemental analyses, magnetic susceptibility, FT IR, UV-Vis, and mass spectroscopy. Complex have been investigated as functional models for catechol oxidase activity by using a catechol as a model substrate. According to the kinetic measurement results, the rate of catechol oxidation follows first order kinetics. Nickel complex has been used in homogenous oxidation of catechol in presence of a green oxidant Hsub2/subO/sub2sub. kinetic parameters were obtained Vsubmax/sub= 2.698×10sup-3/supMSsup-1/sup, iKsubm/sub/i = 7.878M, iksubcat/sub/i= 4.496×10sup-2/supSsup-1/sup and iksubcat/sub/Ksubm/sub/i = 0.5707 Msup-1/supSsup-1/sup.