Risk of Breast Cancer due to Hyperprolactinemia caused by Antipsychotics (Neuroleptics)

摘要

Breast cancer is the most common cancer in females, and is the second most common cause of death. There are several factors which increase a woman's risk for the development of breast cancer. Some reports suggest that neuroleptics and other dopamine antagonists increase the risk of breast cancer due to hyperprolactinemia. There are other reports which suggest that they may decrease the risk of cancer especially rectum, colon and prostate. Additionally, there is evidence that patients with Parkinson's disease have lower rates of breast cancer and other types of malignancies.