A Study On Clinical Features And Cost Incurred By Dengue Syndrome Patients Admitted To Tertiary Care Hospital

摘要

Background: India is one of the seven identified countries in Southeast Asia regularly reporting dengue fever (DF)/dengue haemorrhagic fever (DHF) outbreaks. India may soon transform into a major niche for dengue infection in the future with more and more new areas being struck by dengue epidemics. Objectives: 1) To study the clinical manifestations, trends and outcomes of all confirmed dengue cases admitted to a tertiary care hospital. 2) To study the cost incurred by these patients during hospital stay. Materials and Methods: This record-based study was conducted on 757 serologically (NS1 Ag/ IgM/ IgG) positive dengue cases admitted to KIMS Hospital & Research Centre, Bangalore during January 2012 to December 2012. Required data from the entire laboratory confirmed cases were collected from the Medical Records Department (MRD) and analysed. Results: The seropositive case rate for dengue was 61.5% with NS1 antigen IgM IgG. Males were commonly affected and the most vulnerable age group was found to be between 5 to15 years of age. The median age was 8 years. The percentage of cases presented as dengue fever without warning signs was 88.5%, the remaining being dengue with warning signs and severe dengue. Fever was the most common symptom seen followed by vomiting and abdominal pain. Haemorrhagic manifestations were seen in about 4.5% of cases of which majority presented with petechiae followed by haematemesis. The mortality rate was 8.6%. Conclusion: Increased awareness, better transport facilities and case management according to the WHO guidelines is needed to further reduce mortality and cost burden of dengue cases. Abbreviations: DF - Dengue Fever, DHF - Dengue Haemorrhagic Fever, DSS - Dengue Shock Syndrome, ARDS - Acute Respiratory Distress Syndrome, MODS - Multiple Organ Dysfunction Syndrome.