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Current Management of Achalasia – A Review

机译:眼盲的当前管理-回顾

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Introduction: Achalasia is a rare oesophageal motility disorder characterised by oesophageal aperistalsis and incomplete relaxation on swallowing of the lower oesophageal sphincter. This review aims to identify and critique literature detailing the available management options for these patients and provide an up to date account of current thoughts and controversies in the treatment of achalasia. Methods: An extensive literature search was performed for articles and reviews published on the management of achalasia, using Ovid MEDLINE, Cochrane library and PubMed search databases. Results: The management of achalasia is controversial. Simple options such as pharmacological treatments and Botulinum toxin A injections do not provide sufficient relief of symptoms but may serve to treat those not suitable for surgery or dilatation. However, in those who are deemed suitable, the literature suggests that the optimum treatment is laparoscopic transabdominal Heller myotomy which has demonstrated the best long term results with few complications or perforations. Conclusion: It is not possible to treat the underlying cause of achalasia but only to improve symptoms. Whilst the literature may suggest that the Heller myotomy is the best method to achieve this, it is clear that the outcomes are dependent on surgeon or physician technique and experience. It is important therefore that these patients are treated in a specialist centre with experience with such procedures. Recent advances in surgical and endoscopic technologies, with robotic Heller myotomy and per-oral endoscopic myotomy, provide promising progress for the treatment for achalasia
机译:简介:失语症是一种罕见的食道运动障碍,特征是食道无尖闭症和吞咽下食道括约肌不完全放松。这篇综述旨在鉴定和批评详细介绍这些患者可用治疗方案的文献,并提供有关门失弛缓症治疗的最新思想和争议的最新资料。方法:使用Ovid MEDLINE,Cochrane库和PubMed搜索数据库对关于for门失弛缓症发表的文章和评论进行了广泛的文献搜索。结果:门失弛缓症的治疗存在争议。药物治疗和A型肉毒杆菌毒素注射等简单选择无法充分缓解症状,但可能有助于治疗不适合手术或扩张的患者。但是,对于那些认为合适的人,文献表明,最佳的治疗方法是腹腔镜经腹Heller肌切开术,该方法已被证明是最好的长期结果,几乎没有并发症或穿孔。结论:不可能治疗门失弛缓的根本原因,而只能改善症状。尽管文献可能表明海勒肌切开术是实现这一目标的最佳方法,但很明显,结局取决于外科医生或医师的技术和经验。因此,重要的是要在具有此类程序经验的专科中心对这些患者进行治疗。机器人海勒肌切开术和经口内窥镜肌切开术在外科和内窥镜技术方面的最新进展为门失弛缓症的治疗提供了可喜的进展

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