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Associations between depression subtypes, depression severity and diet quality: cross-sectional findings from the BiDirect Study

机译:抑郁症亚型,抑郁症严重程度与饮食质量之间的关联:BiDirect研究的横断面发现

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Background Depression is supposed to be associated with an unhealthy lifestyle including poor diet. The objective of this study was to investigate differences in diet quality between patients with a clinical diagnosis of depression and population-based controls. Additionally, we aimed to examine effects of specific depression characteristics on diet by analyzing if diet quality varies between patients with distinct depression subtypes, and if depression severity is associated with diet quality. Methods The study included 1660 participants from the BiDirect Study (n?=?840 patients with depression, n?=?820 population-based controls). The psychiatric assessment was based on clinical interviews and a combination of depression scales in order to provide the classification of depression subtypes and severity. Diet quality scores, reflecting the adherence to a healthy dietary pattern, were calculated on the basis of an 18-item food frequency questionnaire. Using analysis of covariance, we calculated adjusted means of diet quality scores and tested differences between groups (adjusted for socio-demographic, lifestyle-, and health-related factors). Results We found no differences in diet quality between controls and patients with depression if depression was considered as one entity. However, we did find differences between patients with distinct subtypes of depression. Patients with melancholic depression reported the highest diet quality scores, whereas patients with atypical depression reported the lowest scores. Depression severity was not associated with diet quality. Conclusions Previous literature has commonly treated depression as a homogeneous entity. However, subtypes of depression may be associated with diet quality in different ways. Further studies are needed to enlighten the diet-depression relationship and the role of distinct depression subtypes.
机译:背景抑郁症可能与不良的生活方式有关,包括不良的饮食习惯。这项研究的目的是调查临床诊断为抑郁症的患者和以人群为基础的对照患者之间饮食质量的差异。此外,我们的目标是通过分析不同抑郁症亚型患者之间的饮食质量是否存在差异,以及抑郁症的严重程度与饮食质量是否相关来检查特定抑郁症特征对饮食的影响。方法该研究包括来自BiDirect研究的1660名参与者(n = 840名抑郁症患者,n = 820名基于人群的对照)。精神病学评估基于临床访谈和抑郁量表的组合,以提供抑郁症亚型和严重程度的分类。饮食质量得分反映了对健康饮食习惯的坚持,是根据18个项目的食物频率问卷计算得出的。使用协方差分析,我们计算了饮食质量得分的调整平均值,并测试了各组之间的差异(针对社会人口统计学,生活方式和健康相关因素进行了调整)。结果我们发现,如果将抑郁症作为一个整体,则对照组和抑郁症患者的饮食质量没有差异。但是,我们确实发现患有不同抑郁症亚型的患者之间存在差异。忧郁症患者的饮食质量得分最高,非典型抑郁症患者的得分最低。抑郁的严重程度与饮食质量无关。结论先前的文献通常将抑郁症视为同质实体。但是,抑郁症的亚型可能以不同的方式与饮食质量相关。需要进一步的研究来启发饮食与抑郁的关系以及独特的抑郁亚型的作用。

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