Rate of Oxidative Stress-Mediated Acceleration of Ageing: Relationship with Habitual Emotional Disposition and Personality Traits

摘要

The study was set out to see if any statistically verifiable correlation exists among oxidative status, personality and rate of ageing. Appropriate measurement scales were Used To Sort 155 Volunteers Into Six Personality Trait Categories, Openness To Experience, Conscienciousness, Extroversion, Agreeableness, Neuroticism, And Psychoticism (OCEAN-P). Blood samples were collected from the volunteers for the determination of the plasma activities of two endogenous antioxidant enzymes-Superoxide Dismutase (SOD) and catalase and of two markers of oxidative damage-Malondialdehyde (MDA) and Erythrocyte Osmotic Fragility (EOF). A factor, "personality factor of Ageing (PFA) here also called the Iyamu factor of ageing named after the originator, was also obtained for each volunteer. The results show that rate of ageing is more affected by oxidative status in persons of four personality types-psychoticism, Neuroticism, Extroversion, and Agreeableness-than in consciencousness and open minded (openness to experience) persons-it also suggests that open minded persons have the slowest rate of ageing.