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Central retinal artery occlusion and cerebral infarction associated with Mycoplasma pneumonia infection in children

机译:小儿视网膜中央动脉阻塞和脑梗死伴支原体肺炎感染

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Background Central retinal artery occlusion (CRAO) is an arterial ischemic stroke, rarely occurred in children accompanied with asymptomatic cerebral infarction and almost never involved in severe pneumonia related to Mycoplasma pneumonia infection. Case presentation An 8-year-old boy with severe pneumonia related to Mycoplasma pneumonia infection that developed loss of vision in the left eye on the 14th day. No light perception and no pupillary reaction to light were found in the left eye. The fundus examination revealed a cherry red spot with severe retinal edema at the macular and peripapillary area, and the optic disc was pale in the left eye but normal in the right eye, suggesting CRAO in the left eye. No obvious neurological symptoms and signs were observed on presentation. Magnetic resonance imaging of the brain showed an abnormal signal of the left lentiform nucleus, caudate nucleus and within the temporal lobe, suggesting an acute cerebral infarction. The analysis of cerebrospinal fluid showed an increasing leukocyte count, but no any pathogenic microorganisms were found. His respiratory symptoms disappeared promptly after therapy, and the patient was discharged after 11?days later, but there was no light in the left eye 2 months after discharge. Conclusion M. pneumoniae infection could be developed the risk for cerebral ischemic stroke, including CRAO in children with severe pneumonia. CRAO is a devastating ophthalmologic event leading to a severe impairment of vision. Patients treated within about 6?h of vision loss had a better visual outcome after the onset of vision loss.
机译:背景技术视网膜中央动脉阻塞(CRAO)是一种动脉缺血性卒中,在无症状性脑梗死的儿童中很少发生,并且几乎从未发生与支原体肺炎感染相关的严重肺炎。病例介绍一名与支原体肺炎感染有关的重症肺炎的8岁男孩在第14天出现左眼视力丧失。左眼未发现光感,也未发现瞳孔对光有反应。眼底检查发现在黄斑区和乳头周围区域有严重的视网膜水肿的樱桃红色斑点,左眼视盘发白,右眼视盘正常,提示左眼CRAO。呈现时未观察到明显的神经系统症状和体征。脑部的磁共振成像显示左半形核,尾状核以及颞叶内的异常信号,提示急性脑梗塞。脑脊液分析显示白细胞计数增加,但未发现任何病原微生物。治疗后他的呼吸道症状迅速消失,患者在11天后出院,但出院后2个月左眼无光。结论肺炎支原体感染可能导致重症肺炎患儿发生脑缺血性卒中,包括CRAO。 CRAO是毁灭性的眼科事件,导致视力严重受损。视力丧失开始后约6小时之内接受治疗的患者的视觉效果更好。

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