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Prevalence of chronic kidney disease and associated factors among the Chinese population in Taian, China

机译:泰安市华人人群中慢性肾脏病的患病率及相关因素

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Background This study was designed to assess the prevalence of chronic kidney disease (CKD) and associated risk factors among the Chinese population in Taian, China. Methods A primary care-based cross-sectional study was conducted in Taian, China, from September to December 2012. Participants selected by a multi-stage stratified cluster sampling procedure were interviewed and tested for hematuria, albuminuria, estimated glomerular filtration rate (eGFR) and other clinical indices. Factors associated with CKD were analyzed by univariate and multivariate logistic regression analysis. Results A total of 14,399 subjects were enrolled in this study. The rates of hematuria, albuminuria and reduced eGFR were 4.20%, 5.25% and 1.89%, respectively. Approximately 9.49% (95% CI: 8.93%–10.85%) of the participants had at least one indicator of CKD, with an awareness of 1.4%. Univariate analyses showed that greater age, body mass index, and systolic and diastolic blood pressure; higher levels of serum creatinine, uric acid, fasting blood glucose, triglycerides, total cholesterol and low-density lipoprotein cholesterol; and lower eGFR were associated with CKD (p?
机译:背景技术本研究旨在评估中国泰安华裔人群中慢性肾脏病(CKD)的患病率和相关危险因素。方法2012年9月至2012年12月,在中国泰安市进行了基于初级保健的横断面研究。对通过多阶段分层整群抽样程序选择的参与者进行了访谈,并进行了血尿,蛋白尿,估计的肾小球滤过率(eGFR)的测试和其他临床指标。通过单因素和多因素logistic回归分析分析与CKD相关的因素。结果本研究共纳入14399名受试者。血尿,蛋白尿和eGFR降低的比率分别为4.20%,5.25%和1.89%。大约9.49%(95%CI:8.93%–10.85%)的参与者至少有一项CKD指标,知晓率为1.4%。单因素分析表明,年龄,体重指数以及收缩压和舒张压均较高。血清肌酐,尿酸,空腹血糖,甘油三酸酯,总胆固醇和低密度脂蛋白胆固醇水平较高;较低的eGFR与CKD相关(每个p <0.05)。多因素分析表明,年龄,女性性别,文化程度,吸烟习惯,收缩压以及糖尿病史,高脂血症,高胆固醇血症和高尿酸血症是CKD的独立危险因素。结论CKD在中国泰安初级保健人群中的流行率很高,尽管知晓率很低。在这一人群中,迫切需要进行健康教育和预防CKD的政策。

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