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The role of DSM-5 borderline personality symptomatology and traits in the link between childhood trauma and suicidal risk in psychiatric patients

机译:DSM-5边缘人格症状和特征在精神病患者儿童创伤与自杀风险之间的联系中的作用

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BackgroundChildhood traumas appear to be linked to suicidal behavior. However, the factors that mediate between these two phenomena are not sufficiently understood. Recent findings suggest that borderline personality disorder (BPD) may explain some of the association. MethodThe present study investigated the potential mediating role of BPD symptomatology and traits between reported childhood trauma and suicidal risk in adult psychiatric outpatients ( N =?124). BPD symptomatology was measured with DSM-5 Section II criterion-counts (SCID-II; Structured Clinical Interview for DSM-IV Axis II), whereas BPD traits were measured with specified DSM-5 Section III traits (PID-5; Personality Inventory for DSM-5). Childhood traumas were self-reported (CTQ; Childhood Trauma Questionnaire), whereas level of suicidal risk was measured with a structured interview (MINI Suicidality Module; Mini International Neuropsychiatric Interview). Mediation effects were tested by bias-corrected (10.000 boot-strapped samples) confidence intervals. ResultsBPD features account for a considerable part of the cross-sectional association between childhood trauma and level of suicidal risk, even when controlling for the influence of gender, age, and educational level. This finding remained stable when testing the model without the suicidality-related BPD criterion and PID-5 items. DSM-5 Section II BPD criterion-counts explained 67% of the total effect, whereas DSM-5 Section III BPD traits accounted for 82% of the total effect. The specific DSM-5 Section III trait facets of “Depressivity” (52%) and “Perceptual Dysregulation” (37%) accounted for most of this effect. ConclusionsThe findings provide preliminary support for the proposed mediation model indicating that BPD features may help explain relations between childhood trauma and elevated suicidal risk in adult life, in particular for DSM-5 Section III personality traits of depressivity (e.g., pessimism, guilt, and shame) and perceptual dysregulation (e.g., dissociation). To reduce the suicidal risk among those with a history of childhood trauma, BPD features (including “Depressivity” and “Perceptual Dysregulation”) might be an important target of assessment, risk management, and treatment. However, other factors are likely to be involved, and a longitudinal and more large-scale design is warranted for a conclusive test of mediation.
机译:背景儿童创伤似乎与自杀行为有关。但是,在这两种现象之间进行调节的因素还没有得到足够的了解。最近的发现表明,边缘性人格障碍(BPD)可能解释了这种关联。方法本研究调查了BPD症状和性状在成人精神科门诊患者中报告的儿童期创伤与自杀风险之间的潜在中介作用(N =?124)。 BPD症状是通过DSM-5第II部分标准计数(SCID-II; DSM-IV第II轴结构化临床访谈)来衡量的,而BPD特质是通过指定的DSM-5 III部分特质(PID-5;针对DSM-5)。儿童创伤是自我报告的(CTQ;儿童创伤问卷),而自杀风险的水平是通过结构化访谈(MINI自杀模块;迷你国际神经精神病访谈)来衡量的。中介效应通过偏差校正(10,000个引导样本)置信区间进行测试。结果即使在控制性别,年龄和文化程度的影响时,BPD功能仍占儿童创伤和自杀风险水平之间的横断面关联的很大一部分。当测试没有自杀相关的BPD标准和PID-5项的模型时,此发现保持稳定。 DSM-5第II部分BPD标准计数解释了总效果的67%,而DSM-5第III部分BPD性状解释了总效果的82%。 DSM-5第III部分特质方面的“抑郁症”(52%)和“知觉失调”(37%)占了大多数。结论该发现为拟议的调解模型提供了初步的支持,表明BPD的功能可能有助于解释儿童创伤与成人生活中自杀风险升高之间的关系,特别是对于DSM-5抑郁的第三节人格特征(例如悲观,内gui和羞愧) )和感知失调(例如,解离)。为了降低有童年创伤史的人的自杀风险,BPD功能(包括“抑郁症”和“知觉失调”)可能是评估,风险管理和治疗的重要目标。但是,可能还会涉及其他因素,因此有必要对纵向和更大范围的设计进行最终的调解测试。

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