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首页> 外文期刊>Brazilian Journal of Medical and Biological Research >Normal skin of HIV-infected individuals contains increased numbers of dermal CD8 T cells and normal numbers of Langerhans cells
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Normal skin of HIV-infected individuals contains increased numbers of dermal CD8 T cells and normal numbers of Langerhans cells

机译:受HIV感染的个体的正常皮肤含有增加数量的真皮CD8 T细胞和正常数量的Langerhans细胞

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摘要

Dysregulation of the skin immune system (SIS) could explain the high prevalence of skin disorders in HIV+ individuals. The present study was carried out to determine whether alterations in the cell population of SIS and epidermal immunoactivation occur in the normal skin of HIV+ individuals. Forty-five biopsies were taken from the normal upper arm skin of 45 HIV+ patients and of 15 healthy controls. HIV+ individuals were divided into three categories according to their CD4 cell blood count (
机译:皮肤免疫系统(SIS)失调可以解释HIV +个体中皮肤疾病的高患病率。进行本研究以确定在HIV +个体的正常皮肤中是否发生SIS细胞群的改变和表皮免疫活化。从45名HIV +患者和15名健康对照的正常上臂皮肤中进行了45次活检。 HIV +个体根据其CD4细胞血细胞计数分为三类(

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