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Effect of an educational intervention on knowledge and attitude regarding pharmacovigilance and consumer pharmacovigilance among community pharmacists in Lalitpur district, Nepal

机译:尼泊尔拉利特布尔区教育干预对社区药剂师有关药物警戒和消费者药物警戒的知识和态度的影响

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BackgroundPharmacovigilance activities are in a developing stage in Nepal. ADR reporting is mainly confined to healthcare professionals working in institutions recognized as regional pharmacovigilance centers. Community pharmacists could play an important role in pharmacovigilance. This study was conducted among community pharmacists in Lalitpur district to examine their knowledge and attitude about pharmacovigilance before and after an educational intervention. MethodsKnowledge and attitude was studied before, immediately after and 6?weeks following the intervention among 75 community pharmacists. Responses were analysed using descriptive and inferential statistics. A pretested questionnaire having twelve and nine statements for assessing knowledge and attitude were used. The overall scores were obtained by adding the ‘knowledge’ and ‘attitude’ scores and ‘overall’ scores were summarized using median and interquartile range. Wilcoxon signed-rank test for repeated samples was used to compare the differences between knowledge and attitude of the pharmacists before and after the educational program. ResultsKnowledge scores [median (interquartile range)] improved significantly between pre-test [39 (44–46)], post-test [44 (44–44)] and retention period of 6?weeks after the intervention [46 (43–46)]. Knowledge score improved immediately post-intervention among both males [44 (41–47)] and females [44 (43–45)] but the retention scores (after 6?weeks) were higher [46 (42–48)] among males. Attitude scores improved significantly among females [46 (44–48)]. The overall scores were higher among pharmacists from rural areas. ConclusionKnowledge and attitude scores improved after the educational intervention. Further studies in other regions of the country are required. The national pharmacovigilance center should promote awareness about ADR reporting among community pharmacists.
机译:背景尼泊尔的药物警戒活动仍处于发展阶段。 ADR报告主要限于在公认的区域性药物警戒中心的机构中工作的医疗保健专业人员。社区药师可以在药物警戒中发挥重要作用。这项研究是在拉利特布尔地区的社区药剂师中进行的,旨在研究他们在进行教育干预之前和之后对药物警戒的知识和态度。方法对75名社区药剂师进行干预之前,之后和6周后的知识和态度进行研究。使用描述性和推断性统计数据分析回应。使用预先测试的问卷,该问卷具有十二个和九个陈述,用于评估知识和态度。总体得分是通过将“知识”和“态度”得分相加得出的,而“总体”得分则使用中位数和四分位数范围进行汇总。对重复样本进行Wilcoxon符号秩检验,以比较教育计划前后药剂师的知识和态度之间的差异。结果在干预前[39(44-46)],测试后[44(44-44)]和保留期6周之间,知识分数[中位数(四分位数间距)]显着提高[46(43-43] 46)]。男性[44(41-47)]和女性[44(43-45)]的干预后知识得分均立即提高,但是男性的保留得分(6周后)更高[46(42-48)] 。女性的态度得分显着提高[46(44-48)]。农村地区药剂师的总体得分较高。结论教育干预后知识和态度得分有所提高。需要在该国其他地区进行进一步研究。国家药物警戒中心应提高社区药剂师对ADR报告的认识。

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