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Trends in the prevalence and management of diagnosed type 2 diabetes 1994–2001 in England and Wales

机译:1994-2001年在英格兰和威尔士的2型糖尿病的诊断和流行趋势

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Background Type 2 diabetes is an important cause of morbidity and mortality. Its prevalence appears to be increasing. Guidelines exist regarding its management. Recommendations regarding drug therapy have changed. Little is known about the influence of these guidelines and changed recommendations on the actual management of patients with type 2 diabetes. This study aims to document trends in the prevalence, drug treatment and recording of measures related to the management of type 2 diabetes; and to assess whether recommended targets can be met. Methods The population comprised subjects registered between 1994 and 2001 with 74 general practices in England and Wales which routinely contribute to the Doctors' Independent Network database. Approximately 500,000 patients and 10,000 type 2 diabetics were registered in each year. Results Type 2 diabetes prevalence rose from 17/1000 in 1994 to 25/1000 in 2001. Drug therapy has changed: use of long acting sulphonylureas is falling while that of short acting sulphonylureas, metformin and newer therapies including glitazones is increasing. Electronic recording of HbA1c, blood pressure, cholesterol and weight have risen steadily, and improvements in control of blood pressure and cholesterol levels have occurred. However, glycaemic control has not improved, and obesity has increased. The percentage with a BMI under 25 kg/m2 fell from 27.0% in 1994 to 19.4% in 2001 (p Conclusion Prevalence of type 2 diabetes is increasing. Its primary care management has changed in accordance with best evidence. Monitoring has improved, but further improvement is possible. Despite this, glycaemic control has not improved, while the prevalence of obesity in the diabetic population is rising.
机译:背景2型糖尿病是发病率和死亡率的重要原因。它的流行似乎正在增加。存在有关其管理的准则。有关药物治疗的建议已更改。关于这些指南的影响以及对2型糖尿病患者的实际管理的变更建议知之甚少。这项研究旨在记录2型糖尿病的流行,药物治疗和措施记录方面的趋势;并评估是否可以达到建议的目标。方法该人群包括1994年至2001年之间在英格兰和威尔士注册的74种常规医学科目,这些常规科目通常会添加到Doctors'Independent Network数据库中。每年约有500,000名患者和10,000名2型糖尿病患者被登记。结果2型糖尿病的患病率从1994年的17/1000上升到2001年的25/1000。药物治疗发生了变化:长效磺酰脲类药物的使用量下降,而短效磺酰脲类,二甲双胍和包括格列酮类在内的新疗法的使用量正在增加。 HbA1c,血压,胆固醇和体重的电子记录稳步上升,并且血压和胆固醇水平的控制得到了改善。但是,血糖控制没有改善,肥胖增加了。 BMI低于25 kg / m 2 的百分比从1994年的27.0%下降到2001年的19.4%(p结论2型糖尿病的患病率正在增加。证据:监测得到了改善,但有可能进一步改善,尽管如此,血糖控制仍未得到改善,而糖尿病人群的肥胖率却在上升。

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