Refractory macular hole repaired by autologous retinal graft and blood clot

摘要

To evaluate the surgical technique using autologous retinal graft (ARG) and autologous blood clot (ABC) for the management of refractory macular holes (MHs). This study was a retrospective, consecutive, interventional case series. Six eyes of 6 patients who underwent vitrectomy combined with ARG and ABC for the treatment of refractory MH were reviewed. Visual and anatomic outcomes were evaluated. The mean age was 59.0?±?9.9?years. All cases had multiple vitreoretinal procedures including vitrectomy and gas fluid exchange before patient presentation. The average numbers of vitrectomies were 2.3?±?0.5, and those of gas fluid exchange were 3?±?1.7. Closure of the macular hole was achieved in four (66.7%) cases at last follow-up. The mean follow-up time was 25.2?±?15.6?months. The averaged BCVA before and after 12?months of the surgery improved from 20/591 to 20/244. This surgical technique using ARG and ABC provide an option for the treatment of refractory MHs.