Determinants of outcome in patients with chronic ischemic left ventricular dysfunction undergone percutaneous coronary interventions

摘要

Background Percutaneous coronary interventions (PCI) in patients with ischemic systolic left ventricular dysfunction (SLVD) are routinely performed although their impact on prognosis remains unclear. Methods We retrospectively evaluated 385 consecutive patients (76?% male, 66?±?9?years) with SLVD (left ventricular ejection fraction [LVEF] ≤40?%) due to chronic coronary artery disease, who underwent PCI between 1999 and 2009, and explored clinical factors associated with higher risk of death or of a composite of death and hospitalization for acute decompensated heart failure (ADHF). Results The median follow-up was 28?months (inter-quartile range 14–46 months). Death and the composite outcome of death and hospitalization for ADHF occurred in 80 (21?%) and 109 (28?%) patients respectively (8.4 and 11.5 per 100 patient-years of follow-up). Insulin-dependent diabetes mellitus (IDDM), multivessel disease, LVEF?p? Conclusions IDDM, symptoms of HF, multivessel disease and LVEF