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Alpha-l-Fucosidase Isoenzyme iso2 from Paenibacillus thiaminolyticus

机译:硫胺酸芽孢杆菌的α1-岩藻糖苷酶同工酶iso2

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Background α- l -Fucosidases are enzymes involved in metabolism of α- l -fucosylated molecules, compounds with a fundamental role in different life essential processes including immune response, fertilization and development, but also in some serious pathological events. According to the CAZy database, these enzymes belong to families 29 and 95. Some of them are also reported to be able to catalyze transglycosylation reactions, during which α- l -fucosylated molecules, representing compounds of interest especially for pharmaceutical industry, are formed.
机译:背景技术α-1-岩藻糖苷酶是参与α-1-岩藻糖基化分子代谢的酶,这些化合物在不同的生命必不可少的过程(包括免疫应答,受精和发育)中以及在某些严重的病理事件中具有基本作用。根据CAZy数据库,这些酶属于29和95族。据报道,其中一些还能够催化转糖基化反应,在此过程中形成了α-1岩藻糖基化分子,这些分子代表了特别是制药工业中感兴趣的化合物。

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