DETECTION OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) FROM ANIMAL AND HUMAN ORIGIN IN BANGLADESH BY POLYMERASE CHAIN REACTION

摘要

Methicillin-resistant Staphylococcus aureus (MRSA) is defined by the presence of the mec A gene, which is considered to have been transferred horizontally from unknown bacterial species to S. aureus . The mec A gene which encodes an additional β-lactam-resistant penicillin-binding protein (PBP), termed PBP-2a (PBP-2’) with reduced binding affinity for β-lactam compounds. We investigated distribution of the mec A gene in a total of 94 clinical strains of S. aureus isolated from both man and animal admitted in Bangladeshi medical hospital as well as Veterinary clinic. The mec A gene was detected by PCR in 25% of human clinical isolates of S. aureus , whereas not a single mec A gene was detected in animal isolates of S. aureus. DOI: http://dx.doi.org/10.3329/bjvm.v9i2.13472