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首页> 外文期刊>Biomarker Insights >Urine Biomarkers Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Kidney Injury Molecule-1 (KIM-1) Have Different Patterns in Heart Failure Exacerbation:
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Urine Biomarkers Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Kidney Injury Molecule-1 (KIM-1) Have Different Patterns in Heart Failure Exacerbation:

机译:尿液生物标志物中性粒细胞明胶酶相关的脂蛋白(NGAL)和肾损伤分子1(KIM-1)在心力衰竭加重中具有不同的模式:

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摘要

Individuals with acute heart failure exacerbation often experience a deterioration in renal function. We sought to determine whether this deterioration is ischemic in nature and detectable by sensitive urine biomarkers neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1). We measured serial biomarker levels and evaluated the associations of these biomarkers with renal recovery in a cohort of hospitalized patients with acute heart failure exacerbation.
机译:患有急性心力衰竭加重的个体经常经历肾功能恶化。我们试图确定这种恶化是否是缺血性的,并可以通过敏感的尿液生物标志物中性粒细胞明胶酶相关的脂蛋白(NGAL)和肾损伤分子1(KIM-1)检测到。我们在一系列住院的急性心力衰竭加重患者中测量了一系列生物标志物的水平,并评估了这些生物标志物与肾脏恢复的相关性。

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