On the Genetic Origin of Complementary Protein Coding

摘要

The relations of protein coding and hydropathy are investigated considering the principles of the molecular recognition theory and Grafstein's hypothesis of the stereochemical origin of the genetic code. It is shown that the coding of RNA and DNA requires 14 dis- tinct groups of codon-anticodon pairs, which define all possible complementary amino acids. The molecular recognition theory is redefined considering the codon-anticodon relations of mRNAs, DNAs, tRNAs and Siemion's mutatin ring of the genetic code. A model of DNA, RNA, RNA and protein coding (and decoding) based on two fundamental properties of DNA/RNA, denoted as complemen- tary and stationary principles, is presented.