Biological membranes for bone repair

摘要

The reconstruction of wide long bone diaphyseal defects is often the major challenge in limb salvage whatever the aetiology of bone loss. Bone defects can occur in case of open diaphyseal fracture or in case of bone non-union (diaphyseal fractures of long bones usually consolidate before the third month. In 10-30% of cases, they do not consolidate after 6 months and are known as 'bone nonunion').