Dynamics And Numerical Simulations In A Production And Development Of Red Blood Cells Model With One Delay

摘要

In this paper, we study an unstructured model of a cellular population in the spirit of Grabosch and Heijmans [Grab-osch A, Heijmans HJAM. Production, development and maturation of red blood cells, A mathematical model. AM-R 8919, ISSN 0924-2953, 1989.] model. The cellular population is described by a system of differential equations with one delay. The basic assumption is that the cell population responsible for the production of blood cells consists of three compartments: the stem cells, the precursor cells, and the blood cells. We prove that the model has two possible steady states and their dynamics (depending on time delay) are studied in term of the local stability, we illustrate these results with numerical simulations for some different values of the time delay.