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Sample Sizes and Effect Sizes are Negatively Correlated in Meta-Analyses: Evidence and Implications of a Publication Bias Against NonSignificant Findings

机译:荟萃分析中样本量和效应量负相关:针对非重大发现的出版物偏倚的证据和含义

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摘要

Meta-analysis involves cumulating effects across studies in order to qualitatively summarize existing literatures. A recent finding suggests that the effect sizes reported in meta-analyses may be negatively correlated with study sample sizes. This prediction was tested with a sample of 51 published meta-analyses summarizing the results of 3,602 individual studies. The correlation between effect size and sample size was negative in almost 80 percent of the meta-analyses examined, and the negative correlation was not limited to a particular type of research or substantive area. This result most likely stems from a bias against publishing findings that are not statistically significant. The primary implication is that meta-analyses may systematically overestimate population effect sizes. It is recommended that researchers routinely examine the n-r scatter plot and correlation, or some other indication of publication bias and report this information in meta-analyses.
机译:荟萃分析涉及跨研究的累积效应,以定性地总结现有文献。最近的发现表明,荟萃分析中报道的效应量可能与研究样本量负相关。通过对51种已发表的荟萃分析样本进行了检验,总结了3,602项个体研究的结果。在几乎80%的荟萃分析中,效应量与样本量之间的相关为负,并且负相关不限于特定类型的研究或实质性领域。该结果很可能源于对发布发现的偏见,这些发现在统计上并不重要。主要含义是荟萃分析可能会系统地高估人口效应的大小。建议研究人员例行检查n-r散点图和相关性,或其他一些出版物偏倚的迹象,并在荟萃分析中报告此信息。

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